Heidi, la bambina delle Alpi (1974)

Heidi, a young girl who has lost her parents early on, is sent to live in the mountains with her grandfather, the Alm-Onji. In the Alps, she befriends goatherd Peter, who looks after the village goats, with whom she has many an adventure. Soon enough, however, Heidi is brought back to the city by her aunt, with whom she lived before her time in the Alps. Now, she is supposed to keep Clara, the daughter of a rich merchant, company and learn reading and writing on the side. Her aunt believes this is a good opportunity for Heidi. But things turn out differently than expected: Clara uses a wheelchair, and Heidi feels more than just uncomfortable in the city. How will Heidi cope with the unfamiliar situation? What about Clara in the wheelchair? What will happen to her grandfather?

Source: www.anisearch.com/anime/2573